Abstract

In this interdisciplinary essay, we reimagine Gilles Deleuze and Félix Guattari’s concept of the _Body without Organs_ (BwO) as a generative framework for understanding embodied cognition, affective flows, and predictive processing across biology, mathematics, and neuroscience. Moving beyond its philosophical origins, the BwO is developed here as a dynamic field of unformed potentiality that cuts across molecular biology, mathematical abstraction (as topological and categorical virtuality), and the neural-affective systems of cognition (as self-organizing predictive agents). We argue that cognition emerges through continuous negotiation with this pre-individual field—a process of sensing, predicting, and becoming shaped by affective micro-events, interoceptive modulations, and relational intensities. Drawing from process philosophy, embodied cognitive science, and dynamical systems theory, we position the BwO as an ontological ground for understanding not just the mind, but the very becoming of bodies, networks, and worlds. This essay proposes a novel conceptual ecology where the embodied brain is not an organized organ, but a fluid interface with the virtual: a topological becoming that reconfigures cognition as improvisation on a field of affective and mathematical possibility. This interdisciplinary framework invites empirical elaboration and theoretical critique from scholars in neuroscience, philosophy, biology, and mathematics. Keywords: Body Without Organs, Embodied Cognition, Predictive Processing, Affective Neuroscience, Process Philosophy, Philosophical Biology, Self-O​r​g​a​