Entry - *617776 - BAGE FAMILY, MEMBER 2; BAGE2 - OMIM - (OMIM.ORG)

 
 
* 617776

BAGE FAMILY, MEMBER 2; BAGE2


Alternative titles; symbols

B MELANOMA ANTIGEN 2


HGNC Approved Gene Symbol: BAGE2

Cytogenetic location: 21p11.2   Genomic coordinates (GRCh38) : 21:10,413,497-10,518,274 (from NCBI)


TEXT

► Cloning and Expression

Using PCR primers based on BAGE1 (BAGE; 605167), Ruault et al. (2002) amplified BAGE2 from human testis and melanoma cDNA libraries. The deduced protein contains 109 amino acids.


► Gene Structure

Ruault et al. (2002) determined that the BAGE2 gene contains 10 exons and spans 76 kb.


► Mapping

By FISH and somatic cell hybrid analyses, Ruault et al. (2002) mapped the BAGE2 gene to chromosome 21p.

Hartz (2017) mapped the BAGE2 gene to chromosome 21p11.2 based on an alignment of the BAGE2 sequence (GenBank AF218570) with the genomic sequence (GRCh38).

► REFERENCES

  1. Hartz, P. A. Personal Communication. Baltimore, Md. 11/15/2017.

  2. Ruault, M., van der Bruggen, P., Brun, M.-E., Boyle, S., Roizes, G., De Sario, A. New BAGE (B melanoma antigen) genes mapping to the juxtacentromeric regions of human chromosomes 13 and 21 have a cancer/testis expression profile. Europ. J. Hum. Genet. 10: 833-840, 2002. [PubMed: 12461691, related citations] [Full Text]


Creation Date:
Patricia A. Hartz : 11/15/2017
Edit History:
mgross : 11/15/2017

* 617776

BAGE FAMILY, MEMBER 2; BAGE2


Alternative titles; symbols

B MELANOMA ANTIGEN 2


HGNC Approved Gene Symbol: BAGE2

Cytogenetic location: 21p11.2   Genomic coordinates (GRCh38) : 21:10,413,497-10,518,274 (from NCBI)


TEXT

Cloning and Expression

Using PCR primers based on BAGE1 (BAGE; 605167), Ruault et al. (2002) amplified BAGE2 from human testis and melanoma cDNA libraries. The deduced protein contains 109 amino acids.


Gene Structure

Ruault et al. (2002) determined that the BAGE2 gene contains 10 exons and spans 76 kb.


Mapping

By FISH and somatic cell hybrid analyses, Ruault et al. (2002) mapped the BAGE2 gene to chromosome 21p.

Hartz (2017) mapped the BAGE2 gene to chromosome 21p11.2 based on an alignment of the BAGE2 sequence (GenBank AF218570) with the genomic sequence (GRCh38).

REFERENCES

  1. Hartz, P. A. Personal Communication. Baltimore, Md. 11/15/2017.

  2. Ruault, M., van der Bruggen, P., Brun, M.-E., Boyle, S., Roizes, G., De Sario, A. New BAGE (B melanoma antigen) genes mapping to the juxtacentromeric regions of human chromosomes 13 and 21 have a cancer/testis expression profile. Europ. J. Hum. Genet. 10: 833-840, 2002. [PubMed: 12461691] [Full Text: https://doi.org/10.1038/sj.ejhg.5200891]


Creation Date:
Patricia A. Hartz : 11/15/2017

Edit History:
mgross : 11/15/2017



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OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2026 Johns Hopkins University.

NOTE: OMIM is intended for use primarily by physicians and other professionals concerned with genetic disorders, by genetics researchers, and by advanced students in science and medicine. While the OMIM database is open to the public, users seeking information about a personal medical or genetic condition are urged to consult with a qualified physician for diagnosis and for answers to personal questions.
OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2026 Johns Hopkins University.
Printed: May 27, 2026