Entry - *613964 - TASTE RECEPTOR, TYPE 2, MEMBER 40; TAS2R40 - OMIM - (OMIM.ORG)

 
 
* 613964

TASTE RECEPTOR, TYPE 2, MEMBER 40; TAS2R40


Alternative titles; symbols

T2R40


HGNC Approved Gene Symbol: TAS2R40

Cytogenetic location: 7q34   Genomic coordinates (GRCh38) : 7:143,222,037-143,223,079 (from NCBI)


TEXT

▼ Description

TAS2R40 belongs to a family of intronless genes that encode highly related bitter taste receptors (TAS2Rs). TAS2Rs are G protein-coupled receptors, which are characterized by 7 transmembrane domains (summary by Fischer et al., 2005). For further information on the TAS2R gene family, see 604791.


► Mapping

By genomic sequence analysis, Fischer et al. (2005) mapped the TAS2R40 gene to a TAS2R gene cluster on chromosome 7q31. Gross (2011) mapped the TAS2R40 gene to chromosome 7q34 based on an alignment of the TAS2R40 sequence (GenBank AF494229) with the genomic sequence (GRCh37).


► REFERENCES

  1. Fischer, A., Gilad, Y., Man, O., Paabo, S. Evolution of bitter taste receptors in humans and apes. Molec. Biol. Evol. 22: 432-436, 2005. Note: Erratum: Molec. Biol. Evol. 22: 1157 only, 2005. [PubMed: 15496549, related citations] [Full Text]

  2. Gross, M. B. Personal Communication. Baltimore, Md. 5/12/2011.


Contributors:
Matthew B. Gross - updated : 5/12/2011
Creation Date:
Patricia A. Hartz : 5/11/2011
Edit History:
terry : 06/08/2012
mgross : 5/12/2011

* 613964

TASTE RECEPTOR, TYPE 2, MEMBER 40; TAS2R40


Alternative titles; symbols

T2R40


HGNC Approved Gene Symbol: TAS2R40

Cytogenetic location: 7q34   Genomic coordinates (GRCh38) : 7:143,222,037-143,223,079 (from NCBI)


TEXT

Description

TAS2R40 belongs to a family of intronless genes that encode highly related bitter taste receptors (TAS2Rs). TAS2Rs are G protein-coupled receptors, which are characterized by 7 transmembrane domains (summary by Fischer et al., 2005). For further information on the TAS2R gene family, see 604791.


Mapping

By genomic sequence analysis, Fischer et al. (2005) mapped the TAS2R40 gene to a TAS2R gene cluster on chromosome 7q31. Gross (2011) mapped the TAS2R40 gene to chromosome 7q34 based on an alignment of the TAS2R40 sequence (GenBank AF494229) with the genomic sequence (GRCh37).


REFERENCES

  1. Fischer, A., Gilad, Y., Man, O., Paabo, S. Evolution of bitter taste receptors in humans and apes. Molec. Biol. Evol. 22: 432-436, 2005. Note: Erratum: Molec. Biol. Evol. 22: 1157 only, 2005. [PubMed: 15496549] [Full Text: https://doi.org/10.1093/molbev/msi027]

  2. Gross, M. B. Personal Communication. Baltimore, Md. 5/12/2011.


Contributors:
Matthew B. Gross - updated : 5/12/2011

Creation Date:
Patricia A. Hartz : 5/11/2011

Edit History:
terry : 06/08/2012
mgross : 5/12/2011



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OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2026 Johns Hopkins University.

NOTE: OMIM is intended for use primarily by physicians and other professionals concerned with genetic disorders, by genetics researchers, and by advanced students in science and medicine. While the OMIM database is open to the public, users seeking information about a personal medical or genetic condition are urged to consult with a qualified physician for diagnosis and for answers to personal questions.
OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2026 Johns Hopkins University.
Printed: May 17, 2026