In this Issue

Table of Contents

Bioethics for the President and Bioethics for the People

Glenn McGee
pp. 1-2
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What Makes Placebo-Controlled Trials Unethical?

Franklin G. Miller, Howard Brody
pp. 3-9
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When Argument Fails

Charles Weijer
pp. 10-11
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Subject Indifference and the Justiªcation of Placebo-Controlled Trials

Robert M. Veatch
pp. 12-13
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Avoiding a Jekyll-And-Hyde Approach to the Ethics of Clinical Research and Practice

Trudo Lemmens, Paul B. Miller
pp. 14-17
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Are Concerns about the Ethics of Placebos a Stalking Horse for Other Issues?

David Healy
pp. 17-19
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Exploiting Subjects in Placebo-Controlled Trials

Nancy S. Jecker
pp. 19-20
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Therapeutic Beneficence and Placebo Controls

Terrence F. Ackerman
pp. 21-22
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Clarifying the Ethics of Clinical Research: A Path toward Avoiding the Therapeutic Misconception

Paul S. Appelbaum
pp. 22-23
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Failure to Conduct a Placebo-Controlled Trial May Be Unethical

Peter J. Cohen
p. 24
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Kathleen Cranley Glass, Duff Waring
pp. 25-26
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Clinical Research Should Not Be Permitted to Escape the Ethical Orbit of Clinical Care

David Steinberg
pp. 27-28
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Exploitation and the Ethics of Clinical Trials

David B. Resnik
pp. 28-30
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I Thought We Were in This Together?

Howard Trachtman
pp. 30-31
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Distinguishing Dilemmas in the Ethics of Placebo-Controlled Trials

Karen Kovach
pp. 32-33
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Placebo Controls: Scientific and Ethical Issues

Charles J. Kowalski
pp. 33-34
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Therapeutic Beneficence and Patient Recruitment in Randomized Controlled Clinical Trials

Howard Mann
pp. 35-36
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Cynthia's Dilemma: Consenting to Heroin Prescription

Louis C. Charland
pp. 37-47
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Who Holds the Leash?

Carl Elliott
p. 48
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Unsafe Presumptions in Clinical Research

Rosamond Rhodes
pp. 49-51
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Resisting the Temptations of Addiction Rhetoric

Christian Perring
pp. 51-52
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Ethics and Heroin Prescription:

Amber S. Orr, Matthew K. Wynia
pp. 52-53
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Commentary: Cynthia's Dilemma

Charles P. O'Brien
pp. 54-55
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Cynthia's Dilemma

Walter Ling
pp. 55-56
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A "Fix" of Reality

Dana Katz, J. R. Neuberger
pp. 56-57
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Addiction and Consent

Laura Weiss Roberts
pp. 58-60
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Choice, Rationality, and Substance Dependence

Ian Freckelton
pp. 60-61
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Authenticity and the Hijacked Brain

Carolyn McLeod
pp. 62-63
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Ethical Evaluation of Heroin-Prescription Research: An Insider's View

Dominique Sprumont
pp. 63-64
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On Being a Bioethicist (review)

Robert Baker
pp. 65-69
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Ward Ethics: Dilemmas for Medical Students and Doctors in Training (review)

Armand H. Matheny Antommaria
pp. 70-71
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Contributors

pp. iii-iv
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