Centromeres are regions of chromosomes that are required for cell division. Complete sequence characterization of centromeres from a diverse group of 65 individuals reveals dynamic and rapid patterns of mutational change, providing information about centromere evolution and function.

A study of more than one million people shows that rare genetic variants that disrupt the FNIP1 gene are associated with a favourable metabolic profile and a roughly 60% lower risk of cardiometabolic disease than the general population. Silencing genes in the FNIP1 pathway in mice induces fat breakdown and reproduces the metabolic benefits associated with the variants in humans.

One reader proposes an alternative to the word ‘television’, and another is enthralled by a meteor, in our weekly dip into Nature’s archive.

Privacy attacks can reveal whether someone’s medical data was used to train an AI model. People who differ from the majority are the most vulnerable to such attacks.