FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term necessary binding region ID (Ontology) MI:0429 (Molecular Interactions)
Definition A sequence range within a molecule identified as being absolutely required for an interaction. The sequence may or may not be in direct physical contact with the interaction partner.[ PubMed:14755292 ]
Also Known As "deletion disrupting interaction" ; "necessary binding site" ; "required to bind"
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 necessary binding region (all annotations which use CV term, excluding "NOT" statements)      92
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mutation decreasing interaction
 |__mutation disrupting interaction___________
biological feature                            |
 |__binding-associated region_________________|
mutation disrupting interaction               |
 |__mutation disrupting interaction strength__|
 |__mutation disrupting interaction rate______|
                                              necessary binding region  92 rec.
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Is a binding-associated region
mutation disrupting interaction
mutation disrupting interaction strength
mutation disrupting interaction rate
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Synonyms
  • "deletion disrupting interaction" EXACT
    "necessary binding site" EXACT
    "required to bind" EXACT PSI-MI-short
Secondary IDs
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