FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term DNA-binding transcription activator activity, RNA polymerase II-specific ID (Ontology) GO:0001228 (Gene Ontology)
Definition A DNA-binding transcription factor activity that activates or increases transcription of specific gene sets transcribed by RNA polymerase II.[ PubMed:20737563 PubMed:27145859 ]
Also Known As "RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription" ; "transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding"
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Records annotated with this term OR any of its CHILD TERMS
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_CELLULAR_COMPONENT       3
Genes (FBgn)  GO_MOLECULAR_FUNCTION     106
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 Gene Groups Genes
 DNA-binding transcription activator activity, RNA polymerase II-specific (all annotations which use CV term, excluding "NOT" statements)       2    106
     contributes_to | DNA-binding transcription activator activity, RNA polymerase II-specific       --       9
     enables | DNA-binding transcription activator activity, RNA polymerase II-specific       --     100
Spanning Tree (Parents/Children) 
DNA-binding transcription factor activity
 |__DNA-binding transcription factor activity, RNA polymerase II-specific__
 |__DNA-binding transcription activator activity___________________________|
                                                                           DNA-binding transcription activator activity, RNA polymerase II-specific  108 rec.
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Is a DNA-binding transcription factor activity, RNA polymerase II-specific
DNA-binding transcription activator activity
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Synonyms
  • "copper ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity involved in positive regulation of transcription" NARROW
    "distal enhancer DNA-binding transcription activator activity, RNA polymerase II-specific" NARROW
    "metal ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity involved in positive regulation of transcription" NARROW
    "metal ion regulated sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription" NARROW
    "proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific" NARROW
    "RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription" NARROW
    "RNA polymerase II distal enhancer sequence-specific DNA-binding transcription factor activity involved in positive regulation of transcription" NARROW
    "RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription" EXACT
    "RNA polymerase II transcriptional activator activity, copper ion regulated proximal promoter sequence-specific DNA binding" NARROW
    "RNA polymerase II transcriptional activator activity, metal ion regulated core promoter proximal region sequence-specific binding" NARROW
    "RNA polymerase II transcriptional activator activity, metal ion regulated proximal promoter sequence-specific DNA binding" NARROW
    "RNA polymerase II transcriptional activator activity, zinc ion regulated core promoter proximal region sequence-specific binding" NARROW
    "RNA polymerase II transcriptional activator activity, zinc ion regulated proximal promoter sequence-specific DNA binding" NARROW
    "sequence-specific distal enhancer binding RNA polymerase II transcription factor activity involved in positive regulation of transcription" NARROW
    "transcriptional activator activity, metal ion regulated sequence-specific DNA binding" NARROW
    "transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding" NARROW
    "transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding" NARROW
    "transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding" NARROW
    "transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding" EXACT
    "zinc ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity involved in positive regulation of transcription" NARROW
Secondary IDs
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Reactome:R-HSA-9856539 "MLXIPL:MLX binds PKLR gene promoter"
Reactome:R-HSA-9856546 "MLXIPL:MLX binds FASN gene promoter"
Reactome:R-HSA-9856548 "MLXIPL:MLX binds ACACB gene promoter"
Reactome:R-HSA-9856549 "MLXIPL:MLX binds ACLY gene promoter"
Reactome:R-HSA-9856550 "MLXIPL:MLX binds ACACA gene promoter"
Reactome:R-HSA-9856604 "MLXIPL:MLX binds AGPAT1 gene promoter"