FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
Help Close All Open All
General Information
Term negative regulation of transcription by RNA polymerase II ID (Ontology) GO:0000122 (Gene Ontology)
Definition Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
Also Known As "down regulation of transcription from RNA polymerase II promoter" ; "down-regulation of transcription from RNA polymerase II promoter" ; "downregulation of transcription from RNA polymerase II promoter" (for all, see Synonyms field below)
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS     223
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 negative regulation of transcription by RNA polymerase II (all annotations which use CV term, excluding "NOT" statements)     223
     involved_in | negative regulation of transcription by RNA polymerase II     223
Spanning Tree (Parents/Children)
regulation of DNA-templated transcription
 |__regulation of transcription by RNA polymerase II____
 |__negative regulation of DNA-templated transcription__|
transcription by RNA polymerase II                      |
 |__regulation of transcription by RNA polymerase II____|
negative regulation of RNA biosynthetic process         |
 |__negative regulation of DNA-templated transcription__|
                                                        negative regulation of transcription by RNA polymerase II  223 rec.
                                                         |__carbon catabolite repression of transcription from RNA polymerase II promoter
                                                         |   |__carbon catabolite repression of transcription from RNA polymerase II promoter by galactose
                                                         |   |__negative regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source
                                                         |__negative regulation of ribosomal protein gene transcription by RNA polymerase II
                                                         |   |__negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to chemical stimulus
                                                         |   |__negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to nutrient levels
                                                         |   |__negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to stress
                                                         |__negative regulation of snRNA transcription by RNA polymerase II
                                                         |__negative regulation of termination of RNA polymerase II transcription
                                                         |   |__negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled
                                                         |__negative regulation of transcription initiation by RNA polymerase II 1 rec.
                                                             |__negative regulation of RNA polymerase II transcription preinitiation complex assembly 1 rec.
Spanning Tree View Settings
Parents/Children
View Depth
hide Relationships
Is a regulation of transcription by RNA polymerase II
negative regulation of DNA-templated transcription
Part of
hide Synonyms & Secondary IDs
Synonyms
  • "down regulation of global transcription from RNA polymerase II promoter" RELATED
    "down regulation of transcription from RNA polymerase II promoter" EXACT
    "down-regulation of global transcription from RNA polymerase II promoter" RELATED
    "down-regulation of transcription from RNA polymerase II promoter" EXACT
    "downregulation of global transcription from RNA polymerase II promoter" RELATED
    "downregulation of transcription from RNA polymerase II promoter" EXACT
    "inhibition of global transcription from RNA polymerase II promoter" RELATED
    "inhibition of transcription from RNA polymerase II promoter" EXACT
    "negative regulation of gene-specific transcription from RNA polymerase II promoter" RELATED
    "negative regulation of global transcription from Pol II promoter" RELATED
    "negative regulation of transcription from Pol II promoter" EXACT
    "negative regulation of transcription from RNA polymerase II promoter" EXACT
    "negative regulation of transcription from RNA polymerase II promoter, global" RELATED
Secondary IDs
hide External Crossreferences & Linkouts
Reactome:R-HSA-2173795 "Downregulation of SMAD2/3:SMAD4 transcriptional activity"
Reactome:R-HSA-8866904 "Negative regulation of activity of TFAP2 (AP-2) family transcription factors"