CRISPR-engineered T cells in patients with refractory cancer.

• Stadtmauer EA ^{1, 2},
• Fraietta JA ^{2, 3, 4, 5, 6},
• Davis MM ^{5, 6},
• Cohen AD ^{7, 2},
• Weber KL ^{2, 8},
• Lancaster E ⁹,
• Mangan PA ⁷,
• Kulikovskaya I ⁵,
• Gupta M ⁵,
• Chen F ⁵,
• Tian L ⁵,
• Gonzalez VE ⁵,
• Xu J ⁵,
• Jung IY ^{4, 5},
• Melenhorst JJ ^{3, 5, 6},
• Plesa G ⁵,
• Shea J ⁵,
• Matlawski T ⁵,
• Cervini A ⁵,
• Gaymon AL ⁵,
• Desjardins S ⁵,
• Lamontagne A ⁵,
• Salas-Mckee J ⁵,
• Fesnak A ^{5, 6},
• Siegel DL ^{5, 6},
• Levine BL ^{5, 6},
• Jadlowsky JK ⁵,
• Young RM ⁵,
• Chew A ⁵,
• Hwang WT ¹⁰,
• Hexner EO ^{7, 2},
• Carreno BM ^{3, 5, 6},
• Nobles CL ⁴,
• Bushman FD ⁴,
• Parker KR ¹¹,
• Qi Y ¹²,
• Satpathy AT ^{11, 12},
• Chang HY ^{11, 13},
• Zhao Y ^{5, 6},
• Lacey SF ^{5, 6},
• June CH ^{14, 3, 5, 6}

Affiliations

• ¹ Division of Hematology-Oncology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. edward.stadtmauer@pennmedicine.upenn.edu cjune@upenn.edu
• ² Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
• ³ Parker Institute for Cancer Immunotherapy, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
• ⁴ Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
• ⁵ Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
• ⁶ Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
• ⁷ Division of Hematology-Oncology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
• ⁸ Department of Orthopaedic Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
• ⁹ Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
• ¹⁰ Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
• ¹¹ Center for Personal Dynamic Regulomes, Stanford University School of Medicine, Stanford, CA, USA
• ¹² Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA
• ¹³ Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA, USA
• ¹⁴ Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. edward.stadtmauer@pennmedicine.upenn.edu cjune@upenn.edu

This work was supported by:

NIA NIH HHS, United States
GrantID: U01 AG066100

NCI NIH HHS, United States
GrantID: R01 CA120409