Mcaulay, Kirsten and Clark, J. Stephen 
ORCID: https://orcid.org/0000-0003-3935-0377
(2017)
Total synthesis of 7-epi-pukalide and 7-acetylsinumaximol B.
Chemistry: A European Journal, 23(41),
pp. 9761-9765.
(doi: 10.1002/chem.201702591)
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Abstract
Convergent total syntheses of the furanocembranoids 7-epi-pukalide and 7-acetylsinumaximol B have been achieved using a one-pot Knoevenagel condensation and thioether-mediated furan-forming reaction. Furan formation proceeds via a sulfur ylide and results in rapid introduction of structural complexity during the coupling of two highly functionalised fragments. The target compounds have been prepared in 16 steps from (R)-perillyl alcohol.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Mcaulay, Kirsten and Clark, Professor Stephen |
| Authors: | Mcaulay, K., and Clark, J. S. |
| College/School: | College of Science and Engineering > School of Chemistry |
| Journal Name: | Chemistry: A European Journal |
| Publisher: | Wiley |
| ISSN: | 0947-6539 |
| ISSN (Online): | 1521-3765 |
| Published Online: | 08 June 2017 |
| Copyright Holders: | Copyright © 2017 Wiley-VCH Verlag |
| First Published: | First published in Chemistry: A European Journal 23(41):9761-9765 |
| Publisher Policy: | Reproduced in accordance with the publisher copyright policy |
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