Brain is a genius French scientist and master criminal who exists as a disembodied brain. Trapped forever in his life support chamber, he has extremely little mobility. His partner and lover is a super-intelligent gorilla named Monsieur Mallah. Niles Caulder is his arch-rival, making him an enemy to the Doom Patrol. He is leader of the Brotherhood of Evil, and has also been a member of the Secret Society of Super-Villains. His Post-Flashpoint counterpart was originally named Ernst.
The Brain was created by Arnold Drake and Bruno Premiani, first appearing in Doom Patrol #86 (1964).
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Pre-Crisis Multiverse
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