MeCP2

طب	MEIS1
	دكتور
	مرض \| جينات الإنسان

MECP2
Available structures
بنك بيانات البروتين	Ortholog search: PDBe RCSB
List of PDB id codes
	1QK9, 3C2I
معرفات
الأسماء المستعارة	MECP2, AUTSX3, MRX16, MRX79, MRXS13, MRXSL, PPMX, RS, RTS, RTT, methyl-CpG binding protein 2
External IDs	الوراثة المندلية البشرية عبر الإنترنت: 300005; معلومات چينوم الفار: 99918; هومولوچين: 3657; چينكاردز: MECP2; OMA:MECP2 - orthologs
Gene location (انسان)
Chr.	X chromosome (human)
End	154,137,103 bp
Gene location (فيران)
Chr.	X chromosome (mouse)
End	73,178,969 bp
تعبير چيني pattern
	Top expressed in
	paraflocculus of cerebellum; ; frontal pole; ; epithelium of colon;
	Top expressed in
	dorsal striatum; ; Region I of hippocampus proper; ; anterior amygdaloid area; ; lateral septal nucleus;
	More reference expression data
	; ; ; ;
	More reference expression data
علم الوجود الجينى
Molecular function	double-stranded methylated DNA binding; transcription corepressor activity; protein domain specific binding; protein N-terminus binding; DNA-binding transcription factor activity; transcription factor binding; siRNA binding; mRNA binding; chromatin binding; ربط بروتيني; ربط دي إن إي; DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA binding; methyl-CpG binding;
Cellular component	postsynapse; سيتوبلازم; ميتوكوندريا; نواة; كروماتين مغاير; خارج خلوي; gamma-tubulin complex; جسيم مركزي; عصارة خلوية; كروماتين; بلازم نووي;
Biological process	negative regulation of neuron apoptotic process; multicellular organismal response to stress; inositol metabolic process; mitochondrial electron transport, ubiquinol to cytochrome c; post-embryonic development; تعلم; استقبال الحس العميق; neuron projection development; regulation of gene expression by genetic imprinting; ضبط نسخ الدنا; نشوء المرض; neuromuscular process controlling posture; adult locomotory behavior; ذاكرة; نسخ الدنا; ventricular system development; neuron maturation; positive regulation of transcription, DNA-templated; glutamine metabolic process; neuromuscular process; histone acetylation; جهد استثاري بعد مشبكي; nervous system process involved in regulation of systemic arterial blood pressure; سلوك اجتماعي; تخلق مشبكي; chemical synaptic transmission; negative regulation of histone methylation; استجابة إجفالية; glucocorticoid metabolic process; dendrite development; negative regulation of transcription by RNA polymerase II; behavioral fear response; respiratory gaseous exchange by respiratory system; cerebellum development; regulation of synaptic plasticity; cardiolipin metabolic process; neuron differentiation; تنظيم التعبير الجيني; حس الألم; negative regulation of transcription, DNA-templated; phosphatidylcholine metabolic process; تعلم بصري; protein localization; response to hypoxia; regulation of gene expression, epigenetic; cellular biogenic amine metabolic process; regulation of respiratory gaseous exchange by nervous system process; brain development; ذاكرة طويلة الأمد; مثيلة الهستونات; negative regulation of histone acetylation; catecholamine secretion; تأييد طويل الأمد; positive regulation of synapse assembly; negative regulation of smooth muscle cell differentiation; positive regulation of histone H3-K9 trimethylation; negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation; mitotic spindle organization; locomotory behavior; ضبط زيادي للتكاثر الخلوي; response to radiation; positive regulation of G2/M transition of mitotic cell cycle; positive regulation of microtubule nucleation; transcription initiation from RNA polymerase II promoter; negative regulation of gene expression; negative regulation of angiogenesis; negative regulation of blood vessel endothelial cell migration; positive regulation of DNA methylation;
	Sources:Amigo / QuickGO
تماثل متسلسل
	4204
	17257
	ENSG00000169057
	ENSMUSG00000031393
	P51608
	Q9Z2D6
	NM_001110792، NM_004992، NM_001316337، XM_024452383، NM_001369391، NM_001369392، NM_001369393، NM_001369394، NM_001386137، NM_001386138، NM_001386139 XM_011531166، NM_001110792، NM_004992، NM_001316337، XM_024452383، NM_001369391، NM_001369392، NM_001369393، NM_001369394، NM_001386137، NM_001386138، NM_001386139
	NM_010788، XM_030251240 NM_001081979، NM_010788، XM_030251240
	NP_001303266، NP_004983، XP_006724882، XP_011529468، XP_024308151، NP_001356320، NP_001356321، NP_001356322، NP_001356323 NP_001104262، NP_001303266، NP_004983، XP_006724882، XP_011529468، XP_024308151، NP_001356320، NP_001356321، NP_001356322، NP_001356323
	NP_034918، XP_030107100 NP_001075448، NP_034918، XP_030107100
	ويكيداتا
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