Thermal behaviour of diclofenac, diclofenac sodium and sodium bicarbonate compositions

@article{Pasquali2007ThermalBO,
  title={Thermal behaviour of diclofenac, diclofenac sodium and sodium bicarbonate compositions},
  author={Irene Pasquali and R. Bettini and Ferdinando Giordano},
  journal={Journal of Thermal Analysis and Calorimetry},
  year={2007},
  volume={90},
  pages={903-907},
  url={https://api.semanticscholar.org/CorpusID:95695262}
}
This work aims to investigate the thermal behaviour of diclofenac, diclofenac sodium, and NaHCO3 both as single components and binary mixtures. In particular, the melting point and latent heat of… 
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9 References

Thermal degradation and melting point determination of diclofenac

A discrepancy was observed between the melting point values recorded under dynamic flow of either dry nitrogen or air, and it has been possible to ascribe this difference in melting points to the formation of three degradation products as a result of intramolecular cyclization and condensation reactions during the heating process in an oxidative atmosphere.

Interaction of pharmaceutical hydrates with supercritical CO2

It was found that all three pharmaceutical hydrates exhibited higher solubility in supercritical CO2 than the relevant anhydrous phases, and diclofenac sodium tetrahydrate represents a peculiar case of chemical interaction with the acid supercritical fluid, mediated by crystal water.

Diclofenac/N-(2-hydroxyethyl)pyrrolidine: a new salt for an old drug.

The mild detergent properties of DHEP were confirmed by the solubilization of lecithin and the formation of mixed micelles with bile salts: these properties appear very interesting in developing new pharmaceutical forms containing DHEP, as a chemical form for the delivery of the active principle diclofenac.

Preparation and characterisation of a range of diclofenac salts.

Determination by DSC of solid–liquid diagrams for polyaromatic – 4,4’diaminodiphenylmethane binary systems

AbstractDiamines are an important group of compounds in different fields of industry and particularly in the synthesis of a number of polymers. In this work, study of binary solid-liquid equilibriums…

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A view and a review of the melting of alkali metal halide crystals

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