DOI:10.14309/ajg.0000000000001278 - Corpus ID: 234768271
ACG Clinical Guidelines: Prevention, Diagnosis, and Treatment of Clostridioides difficile Infections
@article{Kelly2021ACGCG,
title={ACG Clinical Guidelines: Prevention, Diagnosis, and Treatment of Clostridioides difficile Infections},
author={Colleen R. Kelly and Monika Fischer and Jessica R. Allegretti and Kerry L. LaPlante and David B. Stewart and Berkeley N. Limketkai and Neil H. Stollman},
journal={The American Journal of Gastroenterology},
year={2021},
volume={116},
pages={1124 - 1147},
url={https://api.semanticscholar.org/CorpusID:234768271}
}- C. Kelly, M. Fischer, N. Stollman
- Published in American Journal of… 18 May 2021
- Medicine
These guidelines indicate the preferred approach to the management of adults with C. difficile infection and represent the official practice recommendations of the American College of Gastroenterology.
402 Citations
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The management of Clostridioides difficile infection: from empirism to evidence
A synthesis of the most recent international guidelines on the management of CDI is presented, including new data on the clinical efficacy of Fidaxomicin (FDX) and Bezlotoxumab and growing literature on fecal microbiota transplantation (FMT).
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In these rounds, 2 experts, an infectious diseases specialist and a gastroenterologist, discuss antibiotic treatment options for nonsevere disease, the role of fecal microbiota transplantation for fulminant disease, and the use of bezlotoxumab to prevent recurrence in the context of Ms. C, a 48-year-old woman with fulminants C difficile infection.
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New means of management of Clostridioides difficile infection are under development, these including prevention measures (vaccination, population with non-toxigenic strains of the colon, standardized fecal microbiota products) and new antibiotics.
Controversies in the Prevention and Treatment of Clostridioides difficile Infection in Adults: A Narrative Review
In this narrative review, the authors reviewed available literature regarding the prevention or treatment of CDI in adults and focused on disagreements between the IDSA/SHEA and ACG guidelines, as well as articles that have been published since the updates.
Clostridioides difficile Infection: A Clinical Review of Pathogenesis, Clinical Considerations, and Treatment Strategies
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Proper hygiene is indeed noted to be one of the best ways to prevent CDI in the hospital setting and proper prescription of antibiotics can also help reduce the chances of acquiring CDI.
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The incidence of community-acquired CD-АI is increasing compared to nosocomial cases and key risk factors include advanced age, antibiotic use, and hospitalization, while preventative measures for recurrence demonstrate promising outcomes.
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The main priority of C. difficile infection in Indonesia is associated with its prevention, by implementing standard precaution and use of rational antimicrobial.
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A systematic literature review and treatment recommendations based on available evidence for the treatment and prevention of Clostridioides difficile infection are offered.
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An international multidisciplinary panel of experts from the World Society of Emergency Surgery updated its guidelines for management of CDI in surgical patients according to the most recent available literature, including recent changes introduced in the management of this infection.
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