Early Origin and Recent Expansion of Plasmodium falciparum

@article{Joy2003EarlyOA,
  title={Early Origin and Recent Expansion of Plasmodium falciparum},
  author={Deirdre A. Joy and Xiaorong Feng and Jianbing Mu and Tetsuya Furuya and Kesinee Chotivanich and Antoniana Ursine Krettli and May Ho and Alex Wang and Nicholas J. White and Edward Suh and Peter Beerli and Xin-zhuan Su},
  journal={Science},
  year={2003},
  volume={300},
  pages={318 - 321},
  url={https://api.semanticscholar.org/CorpusID:20036560}
}
Genetic evidence is provided for a sudden increase in the African malaria parasite population about 10,000 years ago, followed by migration to other regions on the basis of variation in 100 worldwide mitochondrial DNA sequences.
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26 References

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Dealing with the African 'roots' of the malaria giant means to face both the exceptional stability of the parasite cycle and the risk of disrupting the human natural response with unsustainable interventions, unless it is demonstrated that progress can be achieved in these epidemiological zones through sustainable and cost-effective intermediate steps based on the reduction of infection prevalence.

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It is concluded that the biologic traits, such as periodicity and the capacity to relapse, have limited value for assessing the phylogenetic relationships among Plasmodium species, and it is proposed that the genus Plas modium is polyphyletic.

Y chromosome sequence variation and the history of human populations

Binary polymorphisms associated with the non-recombining region of the human Y chromosome (NRY) preserve the paternal genetic legacy of our species that has persisted to the present, permitting…

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