Dr. Reju-All Advanced Retino-Mela Serum – HPR Retinol Serum for Face – Anti-Aging, Pore Minimizer, Next-Gen Korean Skincare – Gentle & Beginner-Friendly – With Niacinamide 10% and TXA 4% – 30ml

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About this Product

Top highlights

  • PREMIUM K-BEAUTY BACKED BY EXPERTISE — Developed by doctors and pharmacists with a focus on safe, effective ingredients. Trusted in Korea with 1,000,000 units sold in 6 months through 5,000 local pharmacies.
  • GENTLE, LONG-LASTING NEXT-GEN RETINOL HPR – This advanced retinoid delivers visible anti-aging results with 30× greater stability than traditional retinol, while remaining gentle and beginner-friendly for smoother, firmer, youthful-looking skin.
  • VISIBLE RESULTS BEYOND RETINOL AND RETINAL – HPR delivers visible improvements in wrinkles, pores, and skin tone. Clinically proven 8x wrinkle refinement and 13x dark spot correction for smoother, radiant, youthful-looking skin.
  • MELANIN TRIPLE CARE: BLOCKS, PREVENTS, CLEARS — Powered by HPR, Niacinamide, TXA, and Alpha-Bisabolol, this advanced tone-care system helps block melanin, refine uneven tone, and reduce the appearance of spots for a clearer, more even-looking complexion.
  • DERMATOLOGICALLY TESTED — Rated “Excellent” by Germany Dermatest for skin compatibility. Non-comedogenic with 0.00 irritation index. Free from artificial coloring and fragrance, suitable for sensitive skin.
  • HOW TO USE FOR BEST RESULTS – Apply after toner as the second step of your routine: Toner → Retino-Mela Serum → PDRN Cream → Barrier Cream. Best used at night. If used in the morning, always follow with sunscreen for complete protection.
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Safety Information

1)Please read and follow all usage instructions and warnings before use. 2)Do not apply to wounded, eczema-affected, or otherwise problematic areas of skin. 3) Discontinue use and consult a specialist if you experience any abnormal symptoms such as redness, swelling, or itching during or after use, especially after exposure to direct sunlight. 4)Keep out of reach of children. 5) Avoid direct contact with eyes. If contact occurs, rinse thoroughly with water.

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From the brand

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Product Description

Retino-Mela Serum
Retino-Mela Serum
Retino-Mela Serum
Retino-Mela Serum
Retino-Mela Serum
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Customers say

Customers find this skin serum effective for their skincare needs. Users report that their skin feels soft and smoother after use. The serum provides a nice glow and makes skin look more radiant. However, customers have mixed experiences regarding skin irritation and value for money.
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53 customers mention effectiveness, 46 positive, 7 negative
Customers find the skin serum effective for their skincare needs. They describe it as a great retinol product that works well on their skin and consider it a very nice serum that satisfies their skincare requirements.AI Generated from the text of customer reviews
Great product!! Love itRead more
...Tried to mix it with aloe gel to make it lighter. I believe it is a good product but not at all for my skin type. I think I will return it.Read more
Very nice serum, non greasyRead more
Love this cream. It should be used with the barrier cream.Read more
30 customers mention skin feel, 25 positive, 5 negative
Customers find the skin serum leaves their skin feeling soft, smoother, and firmer. They describe the texture as silky when used and creamy, while noting that the product is very gentle on the skin.AI Generated from the text of customer reviews
I hardly write reviews, but this has significantly changed my skin texture, I have oily, combination, sensitive skin, now go figure, with some signs...Read more
Very nice serum, non greasyRead more
Feels lovely on the skin especially after shower. Works pretty good I noticed a lightning of my brown spots, but they have not disappeared....Read more
This serum is very gentle on the skin, and it approves the texture and color...Read more
13 customers mention brightening, 12 positive, 1 negative
The skin serum provides a nice glow and makes skin look more radiant. Customers find it effective for uneven skin tone, with some noting that melasma appears lighter and fading. The product gives a dewy look to the skin.AI Generated from the text of customer reviews
...Works pretty good I noticed a lightning of my brown spots, but they have not disappeared....Read more
13 customers mention skin irritation, 8 positive, 5 negative
The skin serum receives mixed feedback regarding skin irritation. Some customers report that it does not irritate sensitive skin at all and describe it as non-irritating retinol with no irritation. However, others experience adverse reactions, with some mentioning it gave their face a rash, made their skin worse, and caused face stinging.AI Generated from the text of customer reviews
...If anything, it made my skin worseRead more
It gave my face a rash and felt heavey and my skin could not breathe,Read more
...I am in no way a beginner so I was shocked to find that this serum gave me a retinol burn. It messed up my skin barrier....Read more
Caused irritation and redness after a week of use. I also have sensitive skin so couldn’t always fault a product....Read more
8 customers mention value for money, 4 positive, 4 negative
Customers have mixed opinions about the skin serum's value for money. Some find it good value for the money and well worth it, while others consider it pricey and a waste of money.AI Generated from the text of customer reviews
This product works well, but it’s too expensive for such a small amountRead more
Waste of moneyRead more
Too expensiveRead more

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Top reviews from Canada

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  • 5 out of 5 stars
    Verified Purchase

    Great product

    Reviewed in Canada on February 23, 2026
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    I hardly write reviews, but this has significantly changed my skin texture, I have oily, combination, sensitive skin, now go figure, with some signs of aging, my skin feels tight and smooth , I use it daily, I have another skin routing for nite time, I use this plus Salmon DNA Gel Type and the barrier cream from Dr.Reju for my morning routine, its been a huge difference .

    6 people found this helpful
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  • 5 out of 5 stars
    Verified Purchase

    Great product

    Reviewed in Canada on May 29, 2026
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    Great product!! Love it

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  • 4 out of 5 stars
    Verified Purchase

    Recommend and helped overall

    Reviewed in Canada on June 15, 2026
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    Feels lovely on the skin especially after shower. Works pretty good I noticed a lightning of my brown spots, but they have not disappeared. Just be aware this will not make your spots disappear, my face is much smoother feeling and more even, I hike reducing discolouration Recommend -

    One person found this helpful
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  • 3 out of 5 stars
    Verified Purchase

    It gave me retinol burn

    Reviewed in Canada on January 23, 2026
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    I’m someone who has used many different retinols over the years. I am in no way a beginner so I was shocked to find that this serum gave me a retinol burn. It messed up my skin barrier. My face stung and felt bumpy for a week. All I could do was use a barrier repair serum and lotion and it finally fixed it. So buyer beware. You may want to sandwich method this stuff. It’s harsh.

    5 people found this helpful
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  • 5 out of 5 stars
    Verified Purchase

    Very gentle on sensitive skin

    Reviewed in Canada on May 30, 2026
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    This serum is very gentle on the skin, and it approves the texture and color

    I use it every night before my night cream and in the morning my face skin feels smooth and clearer

    One person found this helpful
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  • 5 out of 5 stars
    Verified Purchase

    Rachat assuré

    Reviewed in Canada on July 6, 2026
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    Ma peau a vraiment changé depuis que je l'utilise. J'ai cependant eu un burst les premières 4-5 semaines

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  • 1 out of 5 stars
    Verified Purchase

    Not for sensitive skin

    Reviewed in Canada on March 29, 2026
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    Caused irritation and redness after a week of use. I also have sensitive skin so couldn’t always fault a product. It does feel light and silky when used.

    One person found this helpful
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  • 5 out of 5 stars
    Verified Purchase

    Satisfied skincare

    Reviewed in Canada on April 5, 2026
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    Good product, recommend to buy it

    One person found this helpful
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Top reviews from other countries

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  • 1 out of 5 stars
    Verified Purchase

    Muy poca cantidad para el precio!

    Reviewed in Mexico on June 24, 2026
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    Es súper pequeño el bote, parece muestra.

    Sending feedback...
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  • 5 out of 5 stars
    Verified Purchase

    I Can See Real Results

    Reviewed in the United States on March 9, 2026
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    I bought this serum for myself and I’m really happy with it. The texture is lightweight and absorbs nicely into my skin.

    After using it for a while, I can see visible results. My skin looks smoother and my pores look smaller. It also helps my skin look brighter and healthier.

    Overall, this serum works well for me and I’m glad I tried it. I will keep using it.

    Sending feedback...
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  • 5 out of 5 stars
    Verified Purchase

    Amazing

    Reviewed in the United Arab Emirates on December 31, 2025
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    I'm very thankful very much, my pimples gun and pimple marks feded, just for 1 week I see good result.. I love it ..

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  • 5 out of 5 stars
    Verified Purchase

    Good

    Reviewed in the United Kingdom on July 6, 2026
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    Quick dispatch good item thanks

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  • 5 out of 5 stars
    Verified Purchase

    Love this

    Reviewed in Australia on February 1, 2026
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    I tried many cream, seems this one suits my skin. I am very happy after finally find the cream works on my skin. I bought second bottle when was on sale.

    Sending feedback...
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Product Summary: Dr. Reju-All Advanced Retino-Mela Serum – HPR Retinol Serum for Face – Anti-Aging, Pore Minimizer, Next-Gen Korean Skincare – Gentle & Beginner-Friendly – With Niacinamide 10% and TXA 4% – 30ml

From Dr.Reju-All

4.2 out of 5 stars, 391 ratings

Customer reviews

600+ bought in past month

Price

One-time purchase: $44.90 ( $1.50 / millilitre)

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About this Item

  • PREMIUM K-BEAUTY BACKED BY EXPERTISE — Developed by doctors and pharmacists with a focus on safe, effective ingredients. Trusted in Korea with 1,000,000 units sold in 6 months through 5,000 local pharmacies.
  • GENTLE, LONG-LASTING NEXT-GEN RETINOL HPR – This advanced retinoid delivers visible anti-aging results with 30× greater stability than traditional retinol, while remaining gentle and beginner-friendly for smoother, firmer, youthful-looking skin.
  • VISIBLE RESULTS BEYOND RETINOL AND RETINAL – HPR delivers visible improvements in wrinkles, pores, and skin tone. Clinically proven 8x wrinkle refinement and 13x dark spot correction for smoother, radiant, youthful-looking skin.
  • MELANIN TRIPLE CARE: BLOCKS, PREVENTS, CLEARS — Powered by HPR, Niacinamide, TXA, and Alpha-Bisabolol, this advanced tone-care system helps block melanin, refine uneven tone, and reduce the appearance of spots for a clearer, more even-looking complexion.
  • DERMATOLOGICALLY TESTED — Rated “Excellent” by Germany Dermatest for skin compatibility. Non-comedogenic with 0.00 irritation index. Free from artificial coloring and fragrance, suitable for sensitive skin.
  • HOW TO USE FOR BEST RESULTS – Apply after toner as the second step of your routine: Toner → Retino-Mela Serum → PDRN Cream → Barrier Cream. Best used at night. If used in the morning, always follow with sunscreen for complete protection.

Product description

Retino-Mela Serum

Important Information

Safety Information

1)Please read and follow all usage instructions and warnings before use. 2)Do not apply to wounded, eczema-affected, or otherwise problematic areas of skin. 3) Discontinue use and consult a specialist if you experience any abnormal symptoms such as redness, swelling, or itching during or after use, especially after exposure to direct sunlight. 4)Keep out of reach of children. 5) Avoid direct contact with eyes. If contact occurs, rinse thoroughly with water.

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