LSC

(redirected from Least Significant Change)
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LSCLearning and Skills Council (UK)
LSCLegal Services Commission (UK)
LSCLegal Services Corporation
LSCLogistics and Supply Chain
LSCLocal School Council
LSCLearning Skills Council
LSCLone Star Conference (athletics; various locations)
LSCLondon Study Centre (UK)
LSCLafayette School Corporation (Indiana)
LSCLake Superior College (Duluth, MN)
LSCLiberty Science Center (Jersey City, New Jersey)
LSCLegal Services for Children (various locations)
LSCLichen Simplex Chronicus (dermatology)
LSCLyndon State College (Lyndonville, VT)
LSCLanguage Studies Canada (est. 1962)
LSCLeukemia Stem Cell
LSCLife Safety Code
LSCLIGO Scientific Collaboration
LSCLiquid Scintillation
LSCLean Supply Chain
LSCLink State Control
LSCLimited Slip Coupling
LSCLuxury Sport Coupe
LSCLabel Switch Controller
LSCLocal Service Centre
LSCLab for Scientific Computing
LSCLightweight Stream Control Protocol
LSCLattice Semiconductor Corporation
LSCLuxury Sport Cruiser
LSCLive Sequence Chart
LSCLong String in Context
LSCLocal Support Center
LSCLambda Switch Capable
LSCLarge Scale Central (trains)
LSCLey de Servicio Civil (Spanish: Civil Service Law)
LSCLiquid Scintillation Counter
LSCLarge-Scale Circulation (physics)
LSCLecture Series Committee
LSCLocal Strategic Partnership
LSCLarge-Scale Commercial
LSCLight Switch Cover
LSCLife Skills Coach
LSCLa Salle College (Hong Kong)
LSCLa Salle College
LSCLarge-Scale Change
LSCLongitudinal Space Charge (physics)
LSCLife Science Consulting (Switzerland)
LSCLocal Swimming Committee
LSCLearner Support Centre (various locations)
LSCLaboratory for Scientific Computing (various universities)
LSCLife Sciences Center
LSCLeading Senior Constable (Australia)
LSCLincoln School of Commerce (now Kaplan University)
LSCLeading Spas of Canada
LSCLocal School Committee (various locations)
LSCLogistics Section Chief
LSCLow Sulfur Coal
LSCLump-Sum Contract
LSCLeast Significant Change (bone density)
LSCLithuanian Securities Commission
LSCLeast Significant Character
LSCLab Safety Coordinator (Boston University; Boston, MA)
LSCLawrence Street Center (Colorado)
LSCLaser Scanning Microscope
LSCLogistics Support Center
LSCLucky Sperm Club
LSCLuck Stone Corporation (Virginia)
LSCLive Sequence Chart (sequence diagram UML)
LSCLarge Scale Configuration
LSCLocal Supercluster (astronomy)
LSCLoon State Cyclists (Minnesota)
LSCLa Serena, Chile - La Florida (Airport Code)
LSCLine Scan Camera
LSCLarge Scale Computer
LSCLink State Control (CCS #7/ITU-T)
LSCLatin School of Chicago
LSCLakeview Senior Center (California)
LSCLicensed School Counselor (designation)
LSCLoeb Student Center (New York University)
LSCLoop Start Card
LSCLibrary Society of China
LSCLogistics Support Charge
LSCLeast Squares Circle (shape testing)
LSCLifestyle Shopping Center
LSCLife Support Center
LSCLightning Strike Coalition (Transformers comics)
LSCLondon Seed Capital Limited (London, UK)
LSCLinear Shape Charge
LSCLogistics Support Cost
LSCLower Semi-Continuous Function (mathematical analysis)
LSCLearning Strategies Consortium
LSCLaptop Service Center (various companies)
LSCLoading Standardization Crew
LSCLoad Sharing Control
LSCLoopback Select Code (Hekimian)
LSCLine Signaling Channel (ITU-T)
LSCLaunch Sequence Control
LSCLead System Command
LSCLogistics Steering Committee (US military)
LSCLightguide Shelf Combination (AT&T)
LSCLarson Salvage Company (Bay City, Michigan)
LSCLAN Software Contract
LSCLiteon Semiconductor Corporation
LSCLighting Sub Circuit
LSCLexical Conceptual Structure (linguistics)
LSCLand Surveying Certificate
LSCLongshore Current
LSCLine Side Connection
LSCLogistics Support Concept
LSCLittle Sisters of Christ
LSCLine Side Converter
LSCLarge Solar Concentrator
LSCLake Superior Consulting, LLC (est. 2002; Duluth, MN)
LSCLumbermen's Service Corporation (Austin, TX)
LSCLoire et Sillon Cyclisme (French cycling club)
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References in periodicals archive ?
* To follow-up earlier assessment when the expected change in BMD equals or exceeds the least significant change
Clinical densitometrists weigh in on indications for BMD assessment
To assess whether a change in bone density is "real," he recommended a useful equation called the "least significant change" equation: Multiply the coefficient of variations by three; if the sum is less than 4.5%, then the change may be due to chance.
For example, if the coefficient of variations in hip bone density is 1.5%, the least significant change is 4.5%.
Encouragement aids antiresorptive therapy adherence
The ISCD calls on every DXA center to determine its precision error rate and to calculate and report its least significant change (LSC) score.
Advances favor tests to gauge osteoporosis risk
The ISCD calls on every DXA center to determine its precision error rate and report its least significant change (LSC) score.
Advances favor testing to gauge osteoporosis risk: new ICD-9 code, expanded indications for BMD tests may help detect abnormalities
The critical difference or least significant change is defined as the minimum significant difference (P [less than or equal to] 0.05) between two consecutive bone ALP measurements in the same subject and uses the formula described by Soletormos et al.
These parameters are used to determine the least significant change, or critical difference, needed for a marker to distinguish a true clinical response from normal variation in serial measurements in an individual (21).
Use of bone alkaline phosphatase to monitor alendronate therapy in individual postmenopausal osteoporotic women
For menopausal patients with osteopenia, if a follow-up DXA scan after several years demonstrates a loss in bone density that exceeds the least significant change, one might consider a workup for secondary causes of bone loss and consider medical therapy.
FRAX, too, has limitations
Bauer recommended using the "least significant change" formula.
Stick with antiresorptives, even in nonresponders
The investigators also determined the precision value of the DPX Bravo, defined as the least significant change in BMD with 95% confidence using the International Society for Clinical Densitometry precision calculator.
Imaging unit simplifies hip, spine scans
I should point out that it's important not to overestimate "change." Small differences are not usually biologically relevant, but are simply due to technical error of the procedure, calculated in centers as "least significant change."
Should BMD be used to monitor osteoporosis therapy? (Pro & Con)
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