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Here are just 4 examples:

• CSS Conventions / Code Layout Models
• Are there any CSS standards that I should follow while writing my first stylesheet?
• What is the best method for tidying CSS?
• Best Practices - CSS Stylesheet Formatting

On all 4 my answer has included the advice to download and read Natalie Downe's PDF CSS Systems. (The PDF includes tons of notes not in the slides, so read the PDF!). Take note of her suggestions for organization.

EDIT (2014/02/05) four years later, I'd say:

• Use a CSS pre-processor and manage your files as partials (I personally prefer Sass with Compass, but Less is quite good as well and there are others)
• Read up on concepts like OOCSS, SMACSS, and BEM or getbem.
• Take a look at how popular CSS frameworks like Bootstrap and Zurb Foundation are structured. And don't discount less popular frameworks - Inuit is an interesting one but there are plenty others.
• Combine/minify your files with a build step on a continuous integration server and/or a task runner like Grunt or Gulp.

Here are just 4 examples:

• CSS Conventions / Code Layout Models
• Are there any CSS standards that I should follow while writing my first stylesheet?
• What is the best method for tidying CSS?
• Best Practices - CSS Stylesheet Formatting

On all 4 my answer has included the advice to download and read Natalie Downe's PDF CSS Systems. (The PDF includes tons of notes not in the slides, so read the PDF!). Take note of her suggestions for organization.

EDIT (2014/02/05) four years later, I'd say:

• Use a CSS pre-processor and manage your files as partials (I personally prefer Sass with Compass, but Less is quite good as well and there are others)
• Read up on concepts like OOCSS, SMACSS, and BEM or getbem.
• Take a look at how popular CSS frameworks like Bootstrap and Zurb Foundation are structured. And don't discount less popular frameworks - Inuit is an interesting one but there are plenty others.
• Combine/minify your files with a build step on a continuous integration server and/or a task runner like Grunt or Gulp.

Here are just 4 examples:

• CSS Conventions / Code Layout Models
• Are there any CSS standards that I should follow while writing my first stylesheet?
• What is the best method for tidying CSS?
• Best Practices - CSS Stylesheet Formatting

On all 4 my answer has included the advice to download and read Natalie Downe's PDF CSS Systems. (The PDF includes tons of notes not in the slides, so read the PDF!). Take note of her suggestions for organization.

EDIT (2014/02/05) four years later, I'd say:

• Use a CSS pre-processor and manage your files as partials (I personally prefer Sass with Compass, but Less is quite good as well and there are others)
• Read up on concepts like OOCSS, SMACSS, and BEM
• Take a look at how popular CSS frameworks like Bootstrap and Zurb Foundation are structured. And don't discount less popular frameworks - Inuit is an interesting one but there are plenty others.
• Combine/minify your files with a build step on a continuous integration server and/or a task runner like Grunt or Gulp.

Here are just 4 examples:

• CSS Conventions / Code Layout Models
• Are there any CSS standards that I should follow while writing my first stylesheet?
• What is the best method for tidying CSS?
• Best Practices - CSS Stylesheet Formatting

On all 4 my answer has included the advice to download and read Natalie Downe's PDF CSS Systems. (The PDF includes tons of notes not in the slides, so read the PDF!). Take note of her suggestions for organization.

EDIT (2014/02/05) four years later, I'd say:

• Use a CSS pre-processor and manage your files as partials (I personally prefer Sass with Compass, but Less is quite good as well and there are others)
• Read up on concepts like OOCSS, SMACSS, and BEM or getbem.
• Take a look at how popular CSS frameworks like Bootstrap and Zurb Foundation are structured. And don't discount less popular frameworks - Inuit is an interesting one but there are plenty others.
• Combine/minify your files with a build step on a continuous integration server and/or a task runner like Grunt or Gulp.

This question has been asked/answered several times over on Stack Overflow. Here are just 4 examples:

• CSS Conventions / Code Layout Models
• Are there any CSS standards that I should follow while writing my first stylesheet?
• What is the best method for tidying CSS?
• Best Practices - CSS Stylesheet Formatting

On all 4 my answer has included the advice to download and read Natalie Downe's PDF CSS Systems. (The PDF includes tons of notes not in the slides, so read the PDF!). Take note of her suggestions for organization.

EDIT (2014/02/05) four years later, I'd say:

• Use a CSS pre-processor and manage your files as partials (I personally prefer Sass with Compass, but Less is quite good as well and there are others)
• Read up on concepts like OOCSS, SMACSS, and BEM
• Take a look at how popular CSS frameworks like Bootstrap and Zurb Foundation are structured. And don't discount less popular frameworks - Inuit is an interesting one but there are plenty others.
• Combine/minify your files with a build step on a continuous integration server and/or a task runner like Grunt or Gulp.

Here are just 4 examples:

• CSS Conventions / Code Layout Models
• Are there any CSS standards that I should follow while writing my first stylesheet?
• What is the best method for tidying CSS?
• Best Practices - CSS Stylesheet Formatting

On all 4 my answer has included the advice to download and read Natalie Downe's PDF CSS Systems. (The PDF includes tons of notes not in the slides, so read the PDF!). Take note of her suggestions for organization.

EDIT (2014/02/05) four years later, I'd say:

• Use a CSS pre-processor and manage your files as partials (I personally prefer Sass with Compass, but Less is quite good as well and there are others)
• Read up on concepts like OOCSS, SMACSS, and BEM
• Take a look at how popular CSS frameworks like Bootstrap and Zurb Foundation are structured. And don't discount less popular frameworks - Inuit is an interesting one but there are plenty others.
• Combine/minify your files with a build step on a continuous integration server and/or a task runner like Grunt or Gulp.