10 years ago, it might have been a good idea. Nowadays most parts of the internet (- at least some very popular parts -) have become almost unusable when disabling Javascript in the browser, so today you can expect your users to have Javascript enabled.
And there are lots of frameworks like JQuery to get around browser incompatibilities. IMHO there is no real reason today why you should restrict yourself by not using Javascript for your Website - only reason may be that you don't have any use for it.