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A person requires the company and support of others and society as a whole in order to thrive. The line is from John Donne's Devotions upon Emergent Occasions, published in 1624. Look, I know you're very proud man, but you need to let other people help you if you're in trouble. No man is an island, Dan. It's when our communities rally around us in times of tragedy that we truly appreciate that no man is an island, entire of itself.

To drastically or fundamentally alter one's outlook, circumstances, or way of life. I always dreamed of being a lawyer, so flunking out of law school turned my whole life upside down. Lena's whole life was turned upside down when her mom died, and it took a long time for her to feel any semblance of normality. Such sudden wealth turned his life upside down, as he traded in his shoebox apartment for a luxury mansion in a matter of months.

To drastically or fundamentally alter one's outlook, circumstances, or way of life. I always dreamed of being a lawyer, so flunking out of law school turned my whole world upside down. Lena's whole world was turned upside down when her mom died, and it took a long time for her to feel any semblance of normality. Such sudden wealth turned his world upside down, as he traded in his shoebox apartment for a luxury mansion in a matter of months.