I'm quite new to Python and have been experimenting. So far I have made a simple hangman type game which creates a random word and the user then guesses it. I'd like to know if I've committed any bad practices so I can learn early on what to and not-to do.
#Word Game Python
from random import randint
#Define an alphabet of valid letters
alphabet_file = "alphabet.txt"
#Assign that to a list
alphabet = open(alphabet_file).read().splitlines()
#Define a word
#Find the dictionary
word_file = "words.txt"
#Assign the dictionary to a list
words = open(word_file).read().splitlines()
#Define word based off a random word in the dictionary
word = words[randint(0,len(words))]
#Make the word lower case
word = word.lower()
#Make a list of guesses
guesses = []
#Make a list of correct guesses
correctGuesses = []
#Make a list of incorrect guesses
incorrectGuesses = []
#Set a maximum number of incorrect guesses
incorrectGuessesMax = 7
#A function to help check if something is a number
def isNumber (n):
    try:
        float(n)
        return True
    except ValueError:
        return False
#Returns True if a letter is in a word
def isInWord (letter,word):
    #Make sure letter and word are both strings
    if not letter in alphabet:
        return False
    #Make the letter lower case
    letter = letter.lower()
    #check if the letter is in the word
    if letter in word:
        #if so return true
        return True
    else:
        #Otherwise return false
        return False
#Returns how many times a letter appears in a word
def timesInWord (letter,word):
    #Make the letter Lower Case
    letter = letter.lower()
    #Define a variable to store the times letter is found
    letterCount = 0
    #Check if the letter is in the word
    if isInWord(letter,word):
        #Loop through word to find letter
        for l in range(0,len(word)):
            #If the letter is found
            if letter == word[l]:
                #Add 1 to letterCount
                letterCount += 1
                #Add the guess to the list of correct guesses
                if not isInWord(letter,guesses):
                                    correctGuesses.append(letter)
                                    guesses.append(letter)
        #Return the time the letter was found
        return letterCount
    else:
            if not isInWord(letter,guesses):
                guesses.append(letter)
                incorrectGuesses.append(letter)
            return 0
#Ask the user to input a letter
def getLetter ():
    letter = input("Please enter a letter ")
    #Make sure it's actually a letter(is not a number)
    x = letter
    if isNumber(x):
        print ("Invalid")
        return getLetter()
    #Make sure it's only one letter
    #If it's a word it's ok, that will be chacked later
    if len(letter) == 0:
        print("Invalid")
        return getLetter()
    #If everything is ok, return the letter
    return letter
#A function to print the word based on correct guesses
def printWord(word,guesses):
    #define a printout variable
    printout = ""
    #loop through each letter in the word to check it against the guesses
    for i in range(0,len(word)):
        if word[i] in guesses:
            #if there's a match add the letter to the printout
            printout += word[i]
        else:
            #otherwise fill it with an _
            printout += "_"
    return printout
#Check if word is complete
def checkWord(word,guesses):
    if word == printWord(word,guesses):
        return True
    else:
        return False
#While the word is not complete keep asking for an input
while checkWord(word,correctGuesses) == False:
    #Terminate while loop if there are to many incorrect guesses
    if len( incorrectGuesses ) > incorrectGuessesMax:
        print ("Too many incorrect guesses, the word was: " + word)
        break
    #Receive an input
    guess = getLetter()
    #Chack if the input was a letter or word
    if len(guess) > 1:
        #Check if the guess is equal to the word
        if guess == word:
            #Inform the user of their success
            print("Well Done, You guessed the word correctly in " + str(len(guesses)) + " guesses!")
            #Terminate the loop
            break
        else:
            print(guess + " is not the word you are looking for")
    else:
        #Print how many letters are correct
        print(str(timesInWord(guess,word)) + " out of " + str(len(word)))
    #Print letter guesses
    print ("Your guesses are: " + str(guesses))
    #Print the amount of guesses left
    guessesLeft = incorrectGuessesMax - len(incorrectGuesses)
    guessesLeft += 1
    print ("You have " + str(guessesLeft) + " incorrect guesses left")
    #Print the current state of the word based on correct guesses
    print(printWord(word,correctGuesses)) 
    #Check if the word is completed
    if printWord(word,correctGuesses) == word:
        #Inform the user of their success
        print("Well Done, You guessed the word correctly in " + str(len(guesses)) + " guesses!")
        #Terminate the loop
        break