Timeline for Inefficient DNA heterodimerization script
Current License: CC BY-SA 4.0
12 events
| when toggle format | what | by | license | comment | |
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| Mar 19, 2021 at 13:27 | vote | accept | Apex | ||
| Mar 18, 2021 at 20:40 | answer | added | FirefoxMetzger | timeline score: 1 | |
| Mar 18, 2021 at 2:00 | history | edited | Reinderien | CC BY-SA 4.0 |
added 2 characters in body; edited title
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| Mar 17, 2021 at 22:38 | answer | added | Apex | timeline score: -1 | |
| Mar 17, 2021 at 20:12 | comment | added | Apex | Dear @danzel it would be great if I can get any help from you - many thanks | |
| Mar 17, 2021 at 17:15 | comment | added | Apex |
Same for the next line when reading seq3, if any of respective complements are in seq3 then this seq3 should be discarded, else should be saved and its respective 6mer complements should be added to the list2 and the updated list2 should be [c1,c2,c3,c4,c5,c6,c7,c8,c9,...]
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| Mar 17, 2021 at 17:15 | comment | added | Apex |
@danzel - that was already a good hint, could you please help me to solve this? it should not be like that - meaning let's suppose in the first iteration I have 6mers [m1,m2,m3] from seq1 and their respective complements are should be added to list2 [c1,c2,c3] and when iteration over the seq2 - the script first should look if any of the [c1,c2,c3] are in seq2 if yes then the seq2 should be discarded else should be saved and its respective 6mer complements [c4,c5,c6] should be added to the list2 and the updated list2 should be [c1,c2,c3,c4,c5,c6]
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| Mar 17, 2021 at 16:54 | comment | added | danzel |
I have zero biology knowledge but there is something I suspect may not be intended: every time you find a 6mer, you calculate the reverse complement of each 6mer you have already found and append it to list2. let's number the found 6mers m1, m2, ... and the respective complements c1, c2,...; after the third iteration, list will contain [m1,m2,m3], and list2 will contain [c1,c1,c2,c1,c2,c3]. Could you please clarify if that is intended and, if yes, why?
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| Mar 17, 2021 at 15:53 | history | edited | Jamal | CC BY-SA 4.0 |
deleted 105 characters in body
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| Mar 17, 2021 at 15:37 | comment | added | BCdotWEB | The current question title, which states your concerns about the code, applies to too many questions on this site to be useful. The site standard is for the title to simply state the task accomplished by the code. Please see How do I ask a good question?. | |
| Mar 17, 2021 at 15:20 | review | First posts | |||
| Mar 17, 2021 at 19:52 | |||||
| Mar 17, 2021 at 15:20 | history | asked | Apex | CC BY-SA 4.0 |